By George M. Rodgers
This accomplished quantity discusses the protease ADAMTS13, summarizing the present prestige of simple and scientific examine. The 9 authoritative chapters commence with a old viewpoint by means of exploration of the biochemistry and structure-function relationships of ADAMTS13 in addition to its common functionality in hemostasis (cleavage of von Willebrand factor). rising study issues for ADAMTS13 are lined, together with its power position in angiogenesis and different points of telephone biology. extra subject matters contain laboratory assays for ADAMTS13, inherited ADAMTS13 deficiency, and bought ADAMTS13 deficiency. A bankruptcy on comparable thrombotic microangiopathic (TMA) issues examines the diversities among TMAs linked to ADAMTS13 deficiency and people now not linked to ADAMTS13 deficiency. a last bankruptcy experiences the initial details on rising features of ADAMTS13, comparable to the prestige of recombinant ADAMTS13 items and their capability utility.
Comprehensive in its exploration of the ADAMTS13 protease in disease, ADAMTS13: Biology and illness is an important source for scientific hematologists, transfusion medication physicians, and researchers attracted to hemostasis, vascular biology, biochemistry, and metalloproteases.
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ADAMTS13: Biology and Disease by George M. Rodgers